高血压和精神病的发生
Yauvani Sudarshan1, Bernard M Y Cheung2
1Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Postgraduate medical journal
|June 9, 2023
概括
患有精神病的患者患有高血压,这是代谢综合征的一个组成部分. 早期发现和治疗高血压和代谢综合征对于降低这一群体心血管风险至关重要.
科学领域:
- 医学科学 医学科学 医学科学
- 精神病学是一个精神病学.
- 心脏病学 心脏病学
背景情况:
- 高血压是心血管疾病 (CVD) 的关键危险因素,也是代谢综合征 (MetS) 的组成部分.
- 精神病,特别是精神分裂症谱系障碍,经常与高血压有关 (39%的患病率).
- 抗精神病药物,炎症和自主神经系统功能障碍可能会将精神病和高血压联系起来.
研究的目的:
- 突出精神病患者中高血压的显著流行情况.
- 探索连接精神病,代谢综合征和高血压的机制.
- 强调需要在这个脆弱人群中主动管理代谢综合征和高血压.
主要方法:
- 文献综述和元分析综合.
- 探索精神病症,代谢综合征和心血管风险因素之间的病理生理学联系.
- 分析抗精神病药物对代谢健康的影响.
主要成果:
- 在精神分裂症和相关疾病患者中观察到高血压的高患病率 (39%).
- 肥胖是抗精神病药物的副作用,有助于高血压和其他MetS组件.
- 由Interleukin-6表示的炎症,在精神病,肥胖,MetS和高血压中发挥作用.
结论:
- 在患有精神病的患者中,急需早期检测和管理代谢综合征和高血压.
- 解决这些并发症可以显著降低心血管疾病发病率和死亡率.
- 对接受抗精神病药物治疗的患者来说,专注于预防策略的综合护理至关重要.
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