机会性查无症状左心室功能障碍在2型糖尿病中
Mi Zhou1, Duo Huang1, Yangyang Cheng1
1Cardiology Division, Department of Medicine, University of Hong Kong, Hong Kong, Hong Kong.
Postgraduate medical journal
|June 9, 2023
概括
在2型糖尿病患者中,使用脑性尿素 (NT-proBNP) 的N端前激素对心力衰竭的查是可行的. 这种方法有助于早期发现心血管并发症,改善患者的治疗结果.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 生物标志物研究 生物标志物研究
背景情况:
- 国际指导方针提倡在高风险人群中早期检测心力衰竭 (HF) 的natriuretic生物标志物查.
- 关于将此类查纳入常规临床实践的数据有限.
研究的目的:
- 在被诊断为2型糖尿病 (DM) 的患者中实施左心室功能障碍查计划.
主要方法:
- 在一个专门的DM并发症查中心进行了前性查研究.
- 在2018年至2019年期间招募了1043名2型糖尿病患者.
- 评估了脑内尿素 (NT-proBNP) 的N端前激素水平,并进行了心电图 (ECG).
主要成果:
- 4.1%的患者的NT-proBNP水平升高,表明潜在的HF.
- 4.1%的患者被新诊断为心房动 (AF).
- 随着年龄和功能恶化,NT-proBNP的患病率增加;男性性别,先前的中风,CKD和新的AF与更高的NT-proBNP有关.
结论:
- 在2型糖尿病患者中,NT-proBNP和ECG查很容易实现.
- 这种查有助于早期发现心血管并发症.
- 早期检测可以改善长期患者的治疗结果.
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