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在仿真抗原受体T细胞接受者中发生细胞巨乳病毒感染

Michelly Abreu1, Jaimole Varghese, Minifrida Santiago

  • 1Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer, Houston, Texas.

Journal of the American Association of Nurse Practitioners
|June 9, 2023
PubMed
概括

治疗血液癌症的CAR T细胞治疗可以导致诸如细胞巨乳病毒 (CMV) 这样的感染. 这一案例凸显了治疗后管理CMV再激活的挑战,强调了需要更好的策略的需要.

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Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...