45名新生儿发作患者的临床和脑电学特征
Luying Li1, Yu Deng1, Jin Chen1
1Department of Neurology, Children's Hospital of Chongqing Medical University, NO. 136 Zhongshan 2nd Road, Yuzhong District, Chongqing 400014, China; Ministry of Education Key Laboratory of Child Development and Disorders, NO. 136 Zhongshan 2nd Road, Yuzhong District, Chongqing 400014, China; National Clinical Research Center for Child Health and Disorders (Chongqing), NO. 136 Zhongshan 2nd Road, Yuzhong District, Chongqing 400014, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, NO. 136 Zhongshan 2nd Road, Yuzhong District, Chongqing 400014, China; Chongqing Key Laboratory of Pediatrics, NO. 136 Zhongshan 2nd Road, Yuzhong District, Chongqing 400014, China.
新生儿发作 (NSs) 呈现出与潜在原因相关的多种类型和脑电图 (EEG) 模式. 虽然发作类型和EEG表明病因,但它们不能确定病因.
科学领域:
- 神经学 神经学
- 儿科 儿科 儿科
- 临床神经生理学 临床神经生理学
背景情况:
- 新生儿发作 (NSs) 是儿科的一个关键问题.
- 准确的分类和病因学理解对于有效的管理至关重要.
研究的目的:
- 以回顾分析新生儿发作 (NSs) 的半理学,使用2021年国际抗联盟的分类.
- 研究新生儿病病因和电临床特征之间的关系.
主要方法:
- 在2020年5月至2022年3月期间诊断出NS的45名患者的回顾性分析.
- 包括病因,发作特征,预后,以及ictal/interictal视频脑电图 (EEG) 数据.
主要成果:
- 73.3%的患者有明确的病因;18人只有电图的发作.
- 性和克隆性发作与急性症状发作和新生儿有关;性表示新生儿.
- 与病因相关的间接EEG发现:急性症状性发作中的正常EEG,新生儿发作中的爆发抑制/多焦点放电.
结论:
- 发作语义学和视频EEG为NSs的潜在原因提供了有价值的线索.
- 然而,这些发现本身并不能提供明确的病因学诊断.
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