环境臭氧污染对大量中国人口的长期心脏代谢影响
Li Yang1, Yixiang Zhu2, Bowen Zhao3
1Zhejiang Provincial Research Center for Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Zhejiang Hospital, Hangzhou, Zhejiang, China.
Ecotoxicology and environmental safety
|June 9, 2023
概括
长期暴露于臭氧会增加心脏代谢疾病的风险,包括心血管疾病和中风. 弱势群体如老年人和受教育程度较低的人群更容易受到影响,这凸显了对空气质量控制的需要.
科学领域:
- 环境健康 环境健康
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 臭氧暴露对心脏代谢健康的长期影响的研究有限.
- 臭氧是一种具有潜在健康影响的重要空气污染物.
研究的目的:
- 研究中国东部长期臭氧暴露与心脏代谢疾病和亚临床指标之间的关联.
- 为了确定易受臭氧心脏代谢作用的影响的人群.
主要方法:
- 分析了中国江省 (2014-2021) 的202,042名成年人的队列.
- 基于卫星的建模估计了5年平均住宅臭氧暴露在1x1公里分辨率.
- 混合效应物流和线性回归模型评估了与疾病和生物标志物的关联.
主要成果:
- 臭氧暴露量增加10μg/m3与心脏代谢疾病的几率增加9%有关.
- 发现了与心血管疾病,中风,高血压,失脂症和高甘油三血症的显著关联.
- 血压,胆固醇,葡萄糖和BMI的不良变化也被观察到. 没有与冠心病,心肌梗塞或糖尿病有重大联系.
结论:
- 长期暴露于臭氧会对中国东部的心脏代谢健康产生不利影响.
- 教育程度较低的人,50岁以上的人以及超重/肥胖的人更容易受到伤害.
- 臭氧控制策略对于减少心脏代谢疾病的负担至关重要.
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