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Updated: Jul 27, 2025

Assays for the Degradation of Misfolded Proteins in Cells
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多分子A结合蛋白是一种ATAXIN-2伴侣蛋白,它调节生物分子凝聚物

Steven Boeynaems1, Yanniv Dorone2, Yanrong Zhuang3

  • 1Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA; Therapeutic Innovation Center (THINC), Baylor College of Medicine, Houston, TX 77030, USA; Center for Alzheimer's and Neurodegenerative Diseases (CAND), Texas Children's Hospital, Houston, TX 77030, USA; Dan L Duncan Comprehensive Cancer Center (DLDCCC), Baylor College of Medicine, Houston, TX 77030, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA.

Molecular cell
|June 9, 2023
PubMed
概括

科学家们发现了一种14氨基酸序列,该序列可以作为生物分子凝结的开关,用于像ATAXIN-2这样的蛋白质中. 聚A结合蛋白调节这种开关,为压力颗粒和神经退行性疾病提供了新的见解.

关键词:
在ATXN2中使用.PABPC 公司骨髓缩侧面硬化症 (ALS) 是一种微管结合蛋白质是微管结合蛋白质的组成部分.多QQ多QQ多QQ是什么意思蛋白质聚合蛋白质的聚合物蛋白质相分离的分离过程一个简短的线性图案.脊髓大脑小骨性动脉衰竭压力颗粒是压力颗粒.

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