在慢性淋巴细胞白血病和小淋巴细胞淋巴瘤 (TRANSCEND CLL 004) 中的利索卡巴丁基马拉:多中心,开放式,单臂,第2阶段研究

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Updated: Jul 27, 2025

Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography
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Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography

Published on: February 17, 2022

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Tanya Siddiqi1, David G Maloney2, Saad S Kenderian3

  • 1Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA, USA.

Lancet (London, England)
|June 9, 2023
PubMed
概括

在复发性或耐药性慢性淋巴细胞白血病或小淋巴细胞淋巴瘤患者中,Lisocabtagene maraleucel (lysocel) 显示出显著的完整响应率. 这种CAR- T细胞疗法为患者提供了可行的选择,之前的布鲁顿氨酸激酶抑制剂和venetoclax治疗都失败了.

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