心脏骤停后较高或较低的血压目标:系统性审查与个人患者数据元分析
Ville Niemelä1, Faiza Siddiqui2, Koen Ameloot3
1Department of Anaesthesia and Intensive Care, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Resuscitation
|June 9, 2023
概括
在心脏骤停 (CA) 后准更高的平均动脉压 (MAP) 似乎没有改善存活率或神经恢复. 需要进一步的研究来确定是否存在较小的好处,因为更高的MAP目标并没有增加不良事件.
科学领域:
- 关键护理医学 关键护理医学
- 心血管研究研究心血管研究
- 神经学 神经学
背景情况:
- 目前的指导方针建议在心脏骤停 (CA) 后的平均动脉压 (MAP) 目标>65 mmHg.
- 最近的临床试验已经探索了较高与较低的MAP目标对CA后患者结局的影响.
- 这项研究系统地审查和元分析个人患者数据,以评估这些不同的MAP目标.
结论:
- 准较高的MAP后CA不太可能降低死亡率或改善神经系统的结果.
- 虽然很大程度上治疗效果不太可能,但需要进一步的研究来探索潜在的较小益处.
- 较高的MAP目标与严重不良事件的风险增加无关.
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