在晚期结肠直肠癌中失眠的患病率,严重程度和预测因素
Aaron K Wong1, Dorothy Wang2, David Marco3
1Parkville Integrated Palliative Care Service (A.K.W., D.W., B.L., J.P.), The Royal Melbourne Hospital, Parkville, Victoria, Australia; Department of Medicine, Eastern Hill Campus, (A.K.W., D.M., J.P.), University of Melbourne, Fitzroy, Victoria, Australia.
失眠影响了超过一半的晚期结直肠癌患者,在年轻,移动的个体中有显著的流行. 早期识别和治疗失眠对于改善这一群体的生活质量至关重要.
科学领域:
- 抚慰性护理是一种缓解性护理.
- 在瘤学瘤学.
- 睡眠医学 睡眠医学
背景情况:
- 失眠症在息治疗和晚期癌症患者中经常被忽视和治疗不足.
- 结肠直肠癌是全球领先的癌症,通常与高症状负担有关,但这一群体的失眠仍未得到充分研究.
研究的目的:
- 确定不眠症及其相关因素在患有晚期结肠直肠癌的大群患者中的患病率.
主要方法:
- 一项队列研究分析了来自澳大利亚数据库 (2013-2019) 的18302名晚期结直肠癌患者.
- 使用症状评估得分 (SAS) 评估失眠的严重程度,临床上显著的失眠被定义为SAS ≥3/10.
- 失眠与其他症状/功能评分之间的关联使用验证的问卷进行了检查.
主要成果:
- 任何失眠的患病率为50.5%,临床显著的失眠率为35.6%.
- 在较年轻的患者 (<45岁),具有更高流动性 (AKPS ≥70) 或身体能力 (RUG-ADL ≤5) 的患者,门诊患者和在家生活的患者中观察到更高的失眠患病率.
- 恶心,厌食症和心理困扰是临床显著失眠患者常见的并发症状.
结论:
- 这项研究是首次调查失眠患病率和晚期结直肠癌的相关性.
- 年轻的患者,身体能力较强的患者,住在家里,并经历心理困扰的人有更高的失眠风险.
- 这些发现可以指导早期发现和治疗失眠,以提高晚期结肠直肠癌患者的生活质量.
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