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Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
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评估儿童心脏代谢风险的种族差异
Maria G Tinajero1, Charles Dg Keown-Stoneman2, Laura Anderson3
1University Health Network Biospecimen Services, University Health Network, Toronto, ON, Canada.
Annals of epidemiology
|June 9, 2023
概括
心脏代谢风险 (CMR) 的种族差异出现在童年. 南亚儿童的血压和非高密度胆固醇水平较高,而非洲和东亚儿童的CMR得分低于欧洲儿童.
科学领域:
- 儿科卫生保健 儿科卫生保健
- 心血管研究的心血管研究.
- 公共卫生 公共卫生
背景情况:
- 成年人的心脏代谢状况在不同种族之间存在差异,南亚人特别容易受到影响.
- 关于儿童时期心脏代谢风险 (CMR) 种族差异的证据有限,造成了关键的知识差距.
研究的目的:
- 调查和确定3至11岁儿童心脏代谢风险的种族差异.
- 为了解决缺乏研究的早期生活表现在心脏代谢健康种族差异的表现.
主要方法:
- 对5557名儿童 (3-11岁) 进行了横截面分析.
- 用对共变量调整的多变量线性回归模型来比较14个自我报告的父母种族的CMR结果.
- 主要结局是复合心脏代谢风险评分,包括腰围,静脉血压,葡萄糖,甘油三和高密度胆固醇.
主要成果:
- 与欧洲祖先相比,非洲和东亚血统的儿童的CMR平均得分较低.
- 与欧洲同行相比,南亚血统的儿童表现出明显更高的缩血压和非HDL胆固醇水平.
- 这些心脏代谢风险因素的种族差异在早期和中期儿童中都很明显.
结论:
- 心脏代谢风险在3岁的儿童中存在显著的种族差异.
- 这些发现强调了在儿科心脏代谢风险评估和早期干预策略中考虑种族的重要性.
- 早期识别心脏代谢健康的种族差异对于预防长期心血管疾病至关重要.
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