在中国南部的孕前夫妇中,乙型肝炎病毒感染的流行病学:一个横截面研究
Zhijiang Liang1, Jialing Qiu1, Qianqian Xiang2
1Department of Public Health, Guangdong Women and Children Hospital, Guangzhou, China.
BMJ open
|June 9, 2023
概括
乙型肝炎病毒 (HBV) 感染仍然是一个重大问题,在广东,超过12%的生殖年龄夫妇的HBsAg检测呈阳性. 针对性的疫苗接种和改善健康准入对于预防至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 乙型肝炎病毒 (HBV) 感染是一个全球性的健康问题.
- 生殖年龄的夫妇对于减少HBV传播至关重要.
- 了解这一人口群中的HBV血清流行病学对于控制策略至关重要.
研究的目的:
- 在计划怀孕的夫妇中更新HBV的血清流行病学. 在中国广东省.
- 在这个人群中识别高风险子组.
- 为预防HBV提供公共卫生干预措施的信息.
主要方法:
- 从2014年到2017年,在中国广东进行了一项横截面研究.
- 分析了来自1,283,284个人 (641,642对夫妇) 的数据.
- 血清样本进行了B型肝炎表面抗原 (HBsAg) 和B型肝炎e抗原 (HBeAg) 的检测.
主要成果:
- 发现HBsAg+的患病率为12.56%,HBsAg+和HBeAg+的患病率为3.69%.
- 在广东家庭登记的个人和在珍珠河三角洲以外的人群中发现了更高的患病率.
- 没有伴侣接种疫苗的夫妇显示HBsAg+患病率最高 (24.46%).
结论:
- 在这个高度流行地区的已婚夫妇中发现HBsAg+的显著流行率.
- 需要采取紧急的预防策略,包括改善特定人群获得医疗服务的机会.
- 建议将疫苗接种计划扩展到高风险成年人中.
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