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载体结构在药物处置,有效性和毒性方面的重要作用

Tingting Fu1, Su Zeng1, Qingchuan Zheng2

  • 1College of Pharmaceutical Sciences, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, China (F.Z.); School of Pharmaceutical Sciences, Jilin University, Changchun, China (T.F., Q.Z.); College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China (S.Z., F.Z.); and Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Alibaba-Zhejiang University Joint Research Center of Future Digital Healthcare, Hangzhou, China (F.Z.).

Drug metabolism and disposition: the biological fate of chemicals
|June 9, 2023
PubMed
概括

对ATP结合盒 (ABC) 和溶液载体 (SLC) 载体的结构洞察对于理解药物相互作用至关重要. 计算方法有助于预测这些载体结构,促进药物开发以获得更安全的治疗方法.

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