影响老年移植患者短期生存的因素
Rita M Silva1, Rita Leal2, Maria G Marques2
1Department of Nephrology, Urology, and Kidney Transplantation, Coimbra University Hospital Center, Coimbra, Portugal.
Transplantation proceedings
|June 9, 2023
概括
老年人移植结果存在争议. 诸如较长的感冒缺血时间和接受者心血管疾病等因素预测65岁及以上患者的移植后1年死亡率较高.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 老年医学 老年医学
- 移植手术 移植手术
背景情况:
- 移植为末期病患者提供了更好的生存率和生活质量.
- 老年人 (≥65岁) 是移植的日益增长的人口,但结果仍在争论中.
- 这项研究调查了与老年移植接受者1年死亡率相关的因素.
研究的目的:
- 确定65岁及以上的移植接受者1年死亡率的预测因素.
- 评估捐赠者和接受者因素对这一群体短期移植结果的影响.
主要方法:
- 对147名年龄≥65岁的患者进行了回顾性分析,这些患者在2011年至2020年期间接受了移植.
- 平均随访时间为52.6个月.
- 统计分析以确定移植前和移植后因素与1年死亡率之间的相关性.
主要成果:
- 在65岁以上的患者中,1年死亡率为6.8%.
- 一年死亡率的预测因素包括更长的冷缺血时间,更老的供体年龄,腹腔透析,先前存在的心血管疾病,延迟的移植功能,以及早期的移植后心血管并发症或再住院.
- 没有发现与接受者的年龄,性别,种族,BMI或移植类型有显著的相关性.
结论:
- 严格的移植前评估对于老年移植候选人至关重要.
- 专注于心血管疾病评估和实施严格的排除标准可能会改善老年接受者的结果.
- 识别高风险因素可以指导对老年人移植的临床决策.
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