儿童群体中的反应性淋巴腺病,重点关注淋巴瘤的潜在模仿者
Rachel A Mariani1, Elizabeth L Courville2
1University of Arizona College of Medicine-Phoenix, Dept. of Pathology & Laboratory Medicine, USA.
Seminars in diagnostic pathology
|June 9, 2023
概括
儿科淋巴腺病,往往是良性的,需要仔细评估,以区分从淋巴瘤. 病理学家必须识别那些模仿儿童和青少年恶性瘤的反应性疾病.
科学领域:
- 儿科病理学 儿科病理学
- 血液病理学 血液病理学
- 诊断细胞病理学诊断细胞病理学
背景情况:
- 良性淋巴结核病经常在儿科患者中观察到,并且可以呈现出显著的临床发现.
- 对儿童淋巴结的准确评估需要对形态学,免疫组织化学和临床背景进行彻底评估.
- 区分良性反应性疾病与恶性瘤对于适当的患者管理至关重要.
研究的目的:
- 对儿科患者的非新生病和惰性淋巴细胞增生模式进行审查.
- 突出可能被误诊为淋巴瘤或被纳入淋巴瘤差异诊断中的疾病.
- 为患有儿科淋巴腺病变的病理学家提供指导.
主要方法:
- 在儿童群体中对良性和反应性淋巴腺病的文献综述.
- 专注于形态和免疫组织化学特征.
- 强调模仿淋巴瘤的疾病.
主要成果:
- 在儿童中识别常见的良性淋巴细胞增生模式.
- 可以类似于淋巴瘤的反应性疾病的特征.
- 讨论关键的诊断特征,区分良性和恶性过程.
结论:
- 在儿科患者中熟悉良性淋巴腺病变对于准确诊断至关重要.
- 识别模仿恶性瘤的反应性淋巴细胞增生至关重要.
- 综合性方法结合了形态学,免疫组织化学和临床信息,有助于区分良性与瘤淋巴结核病.
关键词:
毛囊过度增生 毛囊过度增生血液原体 (Hematogones) 是一种血液的组成部分.这就是Kikuchichi的意思.淋巴腺病变 (Lymphadenopathy) 是一种淋巴腺病变.在PTGC中,我们可以看到PTGC.儿科 儿科 儿科生殖中心的渐进转变.这就是ITLP的意义.更多相关视频
06:08Assessment of Chimeric Antigen Receptor T Cell-Associated Toxicities Using an Acute Lymphoblastic Leukemia Patient-Derived Xenograft Mouse Model
Published on: February 10, 2023
1.4K
12:58Expression of Exogenous Cytokine in Patient-derived Xenografts via Injection with a Cytokine-transduced Stromal Cell Line
Published on: May 10, 2017
9.4K
相关概念视频
Primary Lymphoid Organs
1.7K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
1.7K
Secondary Lymphoid Organs
1.7K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
1.7K
Cells of the Adaptive Immune Response
1.1K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
1.1K
Lymphoid Cells and Tissues
1.3K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
1.3K
