[他类药物在因COVID-19而入院的八十岁患者的临床演变中的作用]
Carla Jiménez Martínez1, Victoria Espejo Bares1, Verónica Artiaga de la Barrera1
1Servicio de Cardiología, Hospital Universitario Fundación Alcorcón, Madrid, España.
Medicina clinica
|June 9, 2023
概括
在住院治疗COVID-19之前,静止剂治疗显著降低了八十多岁患者的住院死亡率. 这一发现突显了对抗2019年冠状病毒病的老年人治疗他类药物的潜在益处.
科学领域:
- 老年学是一门学科.
- 传染性疾病 传染性疾病
- 心血管药理学心血管药理学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 在老年人群中存在高死亡风险.
- 以前的研究表明,使用他类药物可能会改善COVID-19的结果.
- 关于他类药物的影响,特别是在80岁以上的COVID-19患者身上,数据有限.
研究的目的:
- 调查COVID-19的80岁以上人群在入院前使用他类药物治疗和住院死亡率之间的关联.
- 分析在最初的流行病浪潮期间住院治疗COVID-19的老年患者的死亡风险因素.
主要方法:
- 一项回顾性队列研究包括258名80岁及以上的患者,他们被确认患有COVID-19.
- 患者被分为两组:在入院前服用他类药物的患者 (n=129) 和未服用他类药物的患者 (n=129).
- 住院死亡率是主要的结局指标.
主要成果:
- 八十岁以上人群的COVID-19在医院住院总死亡率为35.7%.
- 在入院前服用他类药物的患者的死亡率明显较低 (25.6%),与非他类药物使用者 (45.7%) 相比.
- 女性性别,糖尿病和入院前使用他类药物与降低死亡率有关;严重的肺部感染增加了死亡风险.
结论:
- 在第一波期间,入院前的他类药物治疗与八十多岁的COVID-19患者的住院死亡率降低有关.
- 达丁类药物治疗可能会在最老的COVID-19患者群体中提供对严重结局的保护作用.
关键词:
年长的老年人.这是一个古老的老人.80岁或以上的老年人.在 COVID-19 疫情中,美国国家统计局低脂的重要因素之一.医院死亡率 医院死亡率基甲基谷氨基-CoA减少酶抑制剂低脂性致血剂的使用方法氧甲基利-CoA降解剂的抑制剂可以降低这种情况.降脂剂是一种降脂剂.死亡率 死亡率在医院的死亡率.死亡率 死亡率 死亡率八分生殖者 八分生殖者八代人 (英语:Octogenarios) 是指八代人.这就是SARS-CoV-2病毒.类他类药物是一种药物.更多相关视频
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