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Updated: Jul 27, 2025

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通过代谢和结构分析,加强药物目标外发现

Sourav Chowdhury1, Daniel C Zielinski2, Christopher Dalldorf2

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.

Nature communications
|June 9, 2023
PubMed
概括

确定特定的细胞内药物点是具有挑战性的. 这项研究介绍了一种机器学习工作流程,以精确确定非目标,成功识别HPPK作为抗生素CD15-3的非目标.

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