在越南的环境污染与Clostridioides (Clostridium) difficile
Peng An Khun1, Long Duc Phi2, Huong Thi Thu Bui3
1School of Biomedical Sciences, The University of Western Australia, Nedlands 6009, Western Australia, Australia.
Journal of applied microbiology
|June 9, 2023
概括
越南的环境中,Clostridioides difficile (C. difficile) 污染很普遍,特别是在土壤中. 这凸显了环境来源在C. difficile感染流行病学和控制方面的重要性.
科学领域:
- 环境微生物学环境微生物学
- 传染病流行病学 传染病流行病学
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 关于越南环境中的Clostridioides difficile (C. difficile) 的数据有限.
- 了解环境水库对于控制C. difficile感染 (CDI) 至关重要.
研究的目的:
- 为了确定越南环境样本中C. difficile的流行率和分子特征.
- 评估环境中C. difficile分离物的抗微生物敏感性模式.
主要方法:
- 环境样本 (猪便,农场土壤,土豆,医院环境) 被培养为C. difficile.
- 用聚合酶链反应 (PCR) 核型鉴定识别和类型化分离物.
- 对已识别的隔离物进行了抗菌敏感性测试.
主要成果:
- 总体而言,C. difficile的流行率为24.5%,在养猪场土壤 (70-100%) 和医院土壤中检测率高.
- 普遍存在的核糖类型包括RTs 001,009,038和QX574.
- 虽然通常对关键抗生素敏感,但毒性菌株对红红素,四环素和莫西素表现出常见的耐药性;特定的核糖类型具有多药耐药性.
结论:
- 环境C. difficile,特别是受污染的土壤,是越南CDI流行病学的重要因素.
- 污染的土壤对医疗保健机构的感染控制构成挑战.
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