重视偏头痛中单克隆抗体的剂量检测

Linda Al-Hassany1, Nazia Karsan2,3, Christian Lampl4,5

  • 1Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

概括

较高剂量的埃伦乌马布可以通过确保足够的素基因相关 (CGRP) 阻断来改善对非响应者的偏头痛治疗. 重新考虑剂量策略和试验人群对于优化单克隆抗体 (mAb) 治疗至关重要.