在temozolomide治疗期间的淋巴增殖障碍;一个强大的并发症和管理挑战的代表性案例
Daisuke Sato1, Hirokazu Takami2, Shunsaku Takayanagi1
1Department of Neurosurgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
BMC neurology
|June 9, 2023
概括
本案例报告详细介绍了在治疗脑干结质瘤时出现的其他催化性免疫缺陷相关的淋巴增殖障碍 (OIIA-LPD) 的第一例. 停止使用temozolomide导致缓解,突出其在治疗这种罕见并发症中的作用.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 病理学 病理学 病理学
背景情况:
- 淋巴增殖性疾病 (LPDs) 的特点是淋巴细胞的不控制增殖,通常是由免疫缺陷引发的.
- 已知Temozolomide (TMZ) 诱导免疫缺陷,但其与LPD发展的关联之前未被描述.
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