Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Effects of Chemicals: Overview01:27

Effects of Chemicals: Overview

1.3K
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
1.3K
Effects of feedback01:24

Effects of feedback

613
Feedback in control systems plays a critical role in shaping various operational parameters, extending beyond simple error reduction to influence stability, bandwidth, gain, impedance, and sensitivity. Understanding these effects requires examining a basic feedback system characterized by defined input, output, error, and feedback signals.
Feedback significantly modifies the gain of a control system. The gain of a system without feedback is altered by a factor of one plus GH, where G represents...
613
Leveling Effect01:29

Leveling Effect

844
In acid-base chemistry, the leveling effect refers to the limitation imposed by the solvent on the strength of acids and bases in solution. When a base stronger than the solvent's conjugate base is used, it deprotonates the solvent until the base is entirely consumed, making it ineffective against weaker acids. Conversely, an acid stronger than the solvent's conjugate acid protonates the solvent until the acid is depleted, rendering it ineffective against weaker bases. Essentially, the...
844
Law of Effect01:06

Law of Effect

1.5K
B.F. Skinner, a prominent figure in behavioral psychology, introduced operant conditioning by emphasizing the role of consequences in shaping behavior. This theory builds upon the law of effect proposed by Edward Thorndike, which posits that behaviors followed by satisfying outcomes are likely to be repeated. In contrast, those followed by unsatisfying outcomes are less likely to recur.
Edward Thorndike's foundational work involved studying learning in animals, particularly using puzzle...
1.5K
Statistical Significance01:50

Statistical Significance

20.2K
Once data is collected from both the experimental and the control groups, a statistical analysis is conducted to find out if there are meaningful differences between the two groups. A statistical analysis determines how likely any difference found is due to chance (and thus not meaningful). In psychology, group differences are considered meaningful, or significant, if the odds that these differences occurred by chance alone are 5 percent or less. Stated another way, if we repeated this...
20.2K
The Placebo Effect01:54

The Placebo Effect

6.2K
The placebo effect occurs when people's expectations or beliefs influence or determine their experience in a given situation. In other words, simply expecting something to happen can actually make it happen.
6.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Multimatrix Quant<sup>AI</sup>-LFIA: An On-Device Deep-Learning Biosensing Platform with Charge-Transfer-Active Labels for Intelligent Quantitative Analysis.

Analytical chemistry·2026
Same author

A spatiotemporally controllable magnetic microneedle for targeted gastric drug delivery.

Biomaterials science·2026
Same author

Coordination/Assembly Twin-Boosted Lateral Flow Immunochromatographic Assay: Metal-Organic Framework-Mediated Visual Signal Programming for On-Site Ultrasensitive Diagnostics.

Analytical chemistry·2026
Same author

Corrigendum to "Multi-time scale dynamic effective brain networks reveal accelerated brain aging in individuals with major depressive disorder" [J. Psychiatr. Res. 196 (2026) 306-313].

Journal of psychiatric research·2026
Same author

Structural Remodeling of Phage φPNJ-6 Hoc Promotes Adhesion to the Intestinal Epithelium.

Transboundary and emerging diseases·2026
Same author

Phage Φ170 biocontrol of multidrug-resistant <i>Vibrio parahaemolyticus</i> in a zebrafish model.

Microbiology spectrum·2026
Same journal

Correction: Verde et al. Molecular Mechanisms of Protein Aggregation in ALS-FTD: Focus on TDP-43 and Cellular Protective Responses. <i>Cells</i> 2025, <i>14</i>, 680.

Cells·2026
Same journal

Inflammation in Cardiomyopathies: Cellular Mechanisms Across Cardiac Phenotype.

Cells·2026
Same journal

IL-4/IL-13-Driven Dysregulation of Epidermal Lipid Metabolism in Atopic Dermatitis: An Immunometabolic Link Between Type 2 Inflammation and Barrier Dysfunction.

Cells·2026
Same journal

Activity of DNA- and RNA-Guided Prokaryotic Argonautes in Human Mitochondria.

Cells·2026
Same journal

Placental Pathophysiology in Maternal Psychoactive Substance Use: Biological, Clinical, and Forensic Perspectives.

Cells·2026
Same journal

PACAP and Maxadilan (PAC1 Agonist) Influence Plaque Progression, Migratory Ability, and Mitochondrial Morphology and Dynamics in Vascular Smooth Muscle Cells.

Cells·2026
查看所有相关文章

相关实验视频

Updated: Jul 27, 2025

A Task for Assessing the Impact of a Partner on the Speed and Accuracy of Motor Performance in Rats
06:17

A Task for Assessing the Impact of a Partner on the Speed and Accuracy of Motor Performance in Rats

Published on: October 17, 2019

5.0K

影响的效果.

Jinyong Zhou1,2, Keqin Zhang1,3, Jun Gao1,2

  • 1Institute of Animal Husbandry & Veterinary Medicine, Shanghai Academy of Agricultural Sciences, Shanghai 201106, China.

Cells
|June 10, 2023
PubMed
概括
此摘要是机器生成的。

的多糖化合物 (PCP) 提高了上海白猪的精子质量,并减少了冷保存期间的DNA甲基化. 最佳的PCP度 (600-900μg/mL) 提高了活力,运动性和抗氧化功能,有助于保护野猪精液.

关键词:
通过DNA甲基化.波利亚可可斯的多糖化合物 (PCP)上海的白猪上海的白猪抗氧化剂是一种抗氧化剂.精液冷保存 精液冷保存

更多相关视频

Experimental Paradigm for Measuring the Effect of Induced Emotion on Grammar Learning
05:33

Experimental Paradigm for Measuring the Effect of Induced Emotion on Grammar Learning

Published on: January 29, 2020

6.1K
The Joint Effect of Social Comparison and Social Distance on Evaluation of Intertemporal Choice Outcomes in Event-related Potential Studies
08:24

The Joint Effect of Social Comparison and Social Distance on Evaluation of Intertemporal Choice Outcomes in Event-related Potential Studies

Published on: August 25, 2023

776

相关实验视频

Last Updated: Jul 27, 2025

A Task for Assessing the Impact of a Partner on the Speed and Accuracy of Motor Performance in Rats
06:17

A Task for Assessing the Impact of a Partner on the Speed and Accuracy of Motor Performance in Rats

Published on: October 17, 2019

5.0K
Experimental Paradigm for Measuring the Effect of Induced Emotion on Grammar Learning
05:33

Experimental Paradigm for Measuring the Effect of Induced Emotion on Grammar Learning

Published on: January 29, 2020

6.1K
The Joint Effect of Social Comparison and Social Distance on Evaluation of Intertemporal Choice Outcomes in Event-related Potential Studies
08:24

The Joint Effect of Social Comparison and Social Distance on Evaluation of Intertemporal Choice Outcomes in Event-related Potential Studies

Published on: August 25, 2023

776

科学领域:

  • 生殖生物学 生殖生物学
  • 动物科学动物科学
  • 生物化学 生化学

背景情况:

  • 猪精子的冷保存对于养猪计划至关重要.
  • 冷保存可能会对精子质量产生负面影响,并诱导DNA甲基化变化.
  • 的多糖化合物 (PCP) 是具有潜在抗氧化特性的生物活性化合物.

研究的目的:

  • 研究不同度的PCP对冷保存的上海白猪精子质量的影响.
  • 评估PCP对冷保存的野猪精子中的DNA甲基化模式的影响.
  • 确定PCP的最佳度,以改善野猪精液冷保存.

主要方法:

  • 从八只上海白猪收集精液,并用含有不同度PCP (0-1500μg/mL) 的扩展剂进行稀释.
  • 冷保存的精子被解,并对生命力,运动性,等离子体膜完整性,体完整性和线粒体活性进行评估.
  • 分析了抗氧化功能 (ROS,MDA,GSH-Px,SOD,CAT) 和DNA甲基化 (5-mC) 的水平.

主要成果:

  • 在600-1200μg/mL的度下,PCP的补充显著改善了精子的活力,运动性和血膜完整性.
  • 宏粒体完整性和线粒体活性增强了600和900微克/毫升的PCP.
  • PCP降低了氧化应激标志物 (ROS,MDA) 和调节了抗氧化酶活性 (GSH-Px,SOD,CAT),同时显著降低了5-甲基细胞素 (5-mC) 水平.

结论:

  • 补充600-900μg/mL的PCP有效地改善了冷保存的上海白猪精子的质量.
  • 在野猪精子中,PCP减轻了冷诱导的DNA甲基化.
  • PCP代表了一种有前途的策略,用于增强野猪精液冷保存协议.