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Updated: Jul 27, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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微生理模型用于基于机制的预测特异性DILI的机理模型

Sydney Stern1, Hongbing Wang1, Nakissa Sadrieh2

  • 1Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 Penn Street, Baltimore, MD 21201, USA.

Cells
|June 10, 2023
PubMed
概括

通过结合免疫细胞和3D结构,奇异的药物诱导性肝损伤 (iDILI) 模型正在进步. 这些以人为基础的系统旨在改善药物对肝损伤的预测,解决当前临床前模型的局限性.

关键词:
药物诱导的肝损伤是药物诱导的肝毒性 肝毒性 肝毒性一个奇特的独特性.微生理学模型 微生理学模型

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