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Updated: Jul 27, 2025

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
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在罗马尼亚队列中由基因组不稳定性决定的同源重组缺陷得分

Viorica-Elena Rădoi1,2,3,4, Mihaela Țurcan1,3, Ovidiu Virgil Maioru1

  • 1Department of Medical Genetics, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Diagnostics (Basel, Switzerland)
|June 10, 2023
PubMed
概括

同源复合缺陷 (HRD) 测试可以确定受益于PARP抑制剂 (PARPi) 的卵巢癌患者. 没有BRCA突变的HRD阳性患者在PARPi治疗中改善了无进展生存率.

关键词:
罗马尼亚队列的罗马尼亚队列.同类重组缺陷的同类重组缺陷卵巢癌是发生在卵巢的癌症.

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