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刺激性肠综合征的诊断含义 刺激性肠综合征的诊断含义 是在患有炎症性肠病的患者接受手术的独立风险因素
Yuhan Fu1, Nisheet Waghray2, Ronnie Fass2
1Department of Internal Medicine, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH 44109, USA.
刺激性肠综合征 (IBS) 是炎症性肠病 (IBD) 患者发展并发症和接受手术的危险因素. 准确的诊断和管理对于这个患者小组至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 临床流行病学临床流行病学
背景情况:
- 炎症性肠病 (IBD) 和刺激性肠综合征 (IBS) 分享重叠的症状,复杂的诊断和管理.
- 患有IBD缓解的患者可能仍然会出现IBS症状.
- 在IBS患者中,腹部和骨盆外科手术的发生率更高.
研究的目的:
- 为了确定IBS是否是IBD患者手术干预的危险因素.
- 探索IBS在IBD管理中的诊断影响.
主要方法:
- 使用 TriNetX.使用基于人口的队列分析.
- 已确定患有克罗恩病 (CD) + IBS和性结肠炎 (UC) + IBS的患者.
- 在IBD+IBS和IBD单独群体之间比较手术干预风险.
主要成果:
- 患有IBS的IBD患者有更多的胃肠道症状 (p < 0.0001).
- 同时使用IBD和IBS会增加诸如穿孔,出血和等并发症的风险 (p <0.05).
- IBD+IBS患者更有可能接受手术,包括胆管切除和子宫切除 (p < 0.05).
结论:
- IBS是IBD并发症和手术干预的独立风险因素.
- 同时的IBD和IBS可能表明一个具有严重症状的独特子组.
- 准确的诊断和管理对于IBD患者至关重要.
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