在肝脏疾病患者中准确的SARC-F得分
Masahiro Matsui1, Akira Asai1,2, Kosuke Ushiro1
1The Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Takatsuki 569-8686, Osaka, Japan.
Diagnostics (Basel, Switzerland)
|June 10, 2023
概括
在患有肝脏疾病的患者中,SARC-F查工具对肉类的查更有效,得分为1分,而不是4分. 较低的SARC-F得分表明更好的生存率,突出了营养和肉类的预后之间的联系.
科学领域:
- 老年病的医生 老年病的医生
- 肝病学 肝病学是一种肝病学.
- 营养科学 营养科学
背景情况:
- 对于患有肝脏疾病 (LD) 的患者来说,sarcopenia查至关重要.
- SARC-F工具被广泛使用,但其最佳的预后在LD是有争议的.
- 营养状况显著影响LD患者的健康结果.
研究的目的:
- 为了评估SARC-F得分在肝病患者的预后影响.
- 确定最佳的SARC-F截止点来预测LD的存活率.
- 在这个人群中确定与SARC-F得分相关的因素.
主要方法:
- 对269名LD患者 (包括96名肝细胞癌患者) 的回顾性分析.
- 评估SARC-F得分,老年营养风险指数 (GNRI) 和生存数据.
- 多变量分析和接收器操作特征 (ROC) 曲线分析.
主要成果:
- 与SARC-F 0相比,SARC-F评分≥1与更差的预后有关 (一年生存率为78.3%与90.1%,p=0.0181).
- 年龄和GNRI得分是与SARC-F≥1.0相关的重要因素.
- 在ROC分析中发现,预后的最佳SARC-F截止值为1 (AUC=0.60).
结论:
- 在预测肝病患者的预后方面,SARC-F评分≥1比传统的切断值4更有效.
- 由GNRI反映的营养状况与LD的肉类症评估 (SARC-F) 密切相关.
- 使用SARC-F在较低值进行的肉类瘤查可以帮助管理肝脏疾病的预后.
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