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Updated: Jul 27, 2025

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共同对接域中的突变影响了MAP激酶ERK2的催化和稳定

Leonore Novak1, Maria Petrosino2, Alessandra Pasquo3

  • 1Dipartimento di Scienze Biochimiche "A. Rossi Fanelli", Sapienza University of Rome, 00185 Rome, Italy.

Cancers
|June 10, 2023
PubMed
概括

在ERK2对接点的突变会影响其功能和稳定性. 这项研究分析了这些变化如何影响与癌症相关的信号通路,揭示了潜在的治疗点.

关键词:
在ERK2的基础上.这就是MAP激酶.在MAPK1中,MAPK1是MAPK1.癌症突变和蛋白质结构的改变.突变是一种突变.蛋白质的稳定性 蛋白质的稳定性一个单核酸变体.

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