局部麻醉的开始和疼痛感知在血友和血病的条件
Supriya Das1, Shashirekha Govind1, Debkant Jena1
1Department of Conservative Dentistry and Endodontics, Institute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to Be) University, Bhubaneswar 751003, Odisha, India.
Journal of clinical medicine
|June 10, 2023
概括
在血友病患者中,局部麻醉的开始时间略长,但在内牙治疗期间的疼痛感知在血友病患者,血病患者和健康人群中是相似的. 这表明这些患者群体可以实现可比的疼痛管理.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 麻醉学 麻醉学
- 血液学 血液学 血液学
背景情况:
- 在患有血友病和血病等全身性疾病的患者中,控制疼痛和实现有效局部麻醉 (LA) 具有独特的临床考虑.
- 在这些特定患者群体中了解LA发作和疼痛感知的细微差别对于优化内牙治疗方案至关重要.
研究的目的:
- 为了评估和比较局部麻醉 (LA) 的开始和疼痛感知在患有血友病和沙拉西米亚的病人内牙手术期间.
- 评估系统性疾病是否显著改变LA的有效性以及患者在根管治疗期间的疼痛经历.
主要方法:
- 一项比较性研究涉及90名患有下牙不可逆转的胸腔,分为三个组:血友性 (n=30),沙拉西米性 (n=30) 和健康的对照组 (n=30).
- 使用视觉模拟尺度 (VAS) 记录了局部麻醉发病时间和疼痛感知在多个阶段:管理后,脉暴露期间和运河仪器仪表期间.
- 统计分析包括频率分布,ANOVA和线性回归 (p <0.05) 来比较不同组的结果.
主要成果:
- 虽然血友病患者的临床平均LA发病时间较长 (46±34秒),但与thalassemic (42±23秒) 和对照组 (38±12秒) 相比,这些差异在统计学上并不显著.
- 所有组在服用LA后都出现了明显的疼痛减轻 (LA-VAS,p = 0.048).
- 在脉暴露 (PE-VAS,p = 0.82) 或运河仪器仪表 (CI-VAS,p = 0.55) 期间,两组之间没有观察到疼痛感知的统计学上显著差异.
结论:
- 血友病患者可能会经历局部麻醉的发病时间稍长一些,尽管这在本研究中没有统计学意义.
- 在内牙治疗期间,从LA给药到仪器仪表的整体疼痛感知在血友病,血病和健康个体中是可比的.
- 这些发现表明,标准的内牙疼痛管理方案对于患有血友病和沙拉西米亚的患者通常是有效的.
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