患有粉红色的患者眼风险增加:全国性基于人口的队列研究
Kyunghee Chae1, Suyeon Kim2, Sukil Kim1
1Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Journal of clinical medicine
|June 10, 2023
概括
患有粉红症的患者患上青光眼的风险显著增加. 建议对粉红疹患者,特别是50岁以下的患者,女性和高血压患者进行早期查.
科学领域:
- 眼科医生 眼科 眼科
- 皮肤病学 皮肤病学
- 流行病学 流行病学
背景情况:
- 红是一种慢性炎症性皮肤疾病,已知与眼部有关.
- 粉红病和青光眼风险之间的具体联系仍未得到充分研究.
研究的目的:
- 为了调查粉红病与随后患青光眼的风险之间的关联.
- 为了确定患有粉红的特定患者亚组,这些患者可能有更高的青光眼风险.
主要方法:
- 一个全国性的,以人口为基础的,回顾性队列研究.
- 利用来自韩国国家健康保险系统 (NHIS) 数据库 (2002-2015) 的数据.
- 招募了1056名患有疹的患者和10440名匹配的无疹对照.
主要成果:
- 绿内障的发病率在病患者 (1215.4/100,000 PYs) 和对照组 (741.3/100,000 PYs) 中较高.
- 粉红斑明显与眼风险增加有关 (aHR, 1.659; 95% CI, 1.245-2.211).
- 在50岁以下的粉红斑患者 (aHR, 1.943),女性 (aHR, 1.871),高血压患者 (aHR, 1.561) 中,观察到高光眼的风险增加.
结论:
- 粉红斑是发展青光眼的重要危险因素.
- 针对性青光眼查对于粉红病患者至关重要,特别是年轻人,女性和高血压患者.
- 早期检测和管理可以帮助预防与眼相关的视力损失在病患者.
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