高龄人群中中枢修复:心脏年龄与时间年龄有什么区别?
Roya Ostovar1, Filip Schröter1, Martin Hartrumpf1
1Department of Cardiovascular Surgery, Heart Center Brandenburg, Faculty of Health Sciences, University Hospital Brandenburg Medical School "Theodor Fontane", 16321 Bernau, Germany.
Journal of clinical medicine
|June 10, 2023
概括
心脏衰老显著影响手术结果,老年患者由于心脏恶化而经历更糟糕的结果. 这凸显了针对老年人口心脏衰老的干预措施的必要性.
科学领域:
- 心脏病学 心脏病学
- 老年医学 老年医学
- 心脏外科手术 心脏外科手术
背景情况:
- 高龄是心脏手术中不良结果的已知危险因素.
- 老年人的脆弱性和多病性导致手术风险.
- 这项研究调查了心脏衰老是否与时间衰老不同.
研究的目的:
- 为了确定是否有明显的心脏衰老模式.
- 为了比较老年人和年轻患者之间的心脏参数和手术结果.
- 分析心脏衰老对不同年龄组手术结果的影响.
主要方法:
- 倾向性得分匹配比较了115名老年人 (≥80岁) 和345名年轻人 (<80岁).
- 患者与心脏和非心脏疾病以及风险概况相匹配.
- 分析了心脏参数,健康状况和术后结果,并进一步按年龄几十年划分.
主要成果:
- 老年人显示显著减少三环状平面缩外流 (TAPSE),更多的腹功能障碍和更高的NT-proBNP水平.
- 老年患者的左心室和左心房直径更大.
- 在老年人中,住院死亡率和术后并发症明显高于老年人,结果在几十年内恶化.
结论:
- 老年人表现出更大的心脏衰老和多病症,导致死亡风险显著增加和复杂的术后过程.
- 心脏衰老是一个独特的临床实体,影响手术结果.
- 对心脏衰老的预防和治疗策略对于老龄化社会至关重要.
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