复杂的COPD与COVID-19之间的关联
Nikhil T Awatade1, Peter A B Wark1,2, Andrew S L Chan3,4
1Immune Health Program, Hunter Medical Research Institute and University of Newcastle, Newcastle 2305, Australia.
Journal of clinical medicine
|June 10, 2023
概括
慢性阻塞性肺病 (COPD) 患者面临更高风险的严重COVID-19结果. 本综述审查了COPD的研究.
科学领域:
- 肺部医学 肺部医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 慢性阻塞性肺病 (COPD) 是全球主要的疾病和死亡原因.
- 慢性肺炎患者可能有严重COVID-19结局的风险增加,但对SARS-CoV-2感染的易感性不太清楚.
研究的目的:
- 提供COPD和COVID-19之间的复杂关系的最新审查.
- 评估COPD患者对SARS-CoV-2和COVID-19疾病严重程度的敏感性的证据.
- 讨论影响COPD-COVID-19关联和管理策略的因素.
主要方法:
- 综合文献综述. 这是一个全面的文献综述.
- 对COPD患者对SARS-CoV-2感染的敏感性研究的审查.
- 对COPD患者COVID-19严重程度的证据分析.
主要成果:
- 大多数研究表明,先前存在的COPD与更糟糕的COVID-19结果有关.
- 关于COPD患者对SARS-CoV-2感染的易感性,存在相互矛盾的结果.
- 讨论了像吸烟,吸入皮质类固醇和社会经济/遗传因素等混因素.
结论:
- 慢性肺炎和COVID-19之间的关联是复杂的,需要进一步研究.
- 在大流行期间,仔细管理COPD患者至关重要,以减轻严重的COVID-19风险.
- 公共卫生措施在传染病爆发期间显著影响COPD患者的护理.
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