与心肌桥相关的MINOCA:发病,诊断和治疗
Riccardo Rinaldi1, Giuseppe Princi1, Giulia La Vecchia1
1Department of Cardiovascular and Pulmonary Sciences, Catholic University of the Sacred Heart, 00168 Rome, Italy.
Journal of clinical medicine
|June 10, 2023
概括
心肌架桥 (MB) 可以通过各种机制引起心肌梗塞与非阻塞冠状动脉 (MINOCA). 本综述详细介绍了MB相关的MINOCA病理生理学,诊断和量身定制的治疗策略.
科学领域:
- 心脏病学 心脏病学
- 病理生理学 病理生理学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 心肌桥架 (MB) 是最常见的先天性冠状动脉异常.
- MB越来越多地被认为是非阻塞冠状动脉 (MINOCA) 心肌梗塞的原因.
- 在MB患者中,MINOCA是由各种机制引起的,包括冠状动脉,斑块破坏和自发冠状动脉剖析.
研究的目的:
- 审查关于MINOCA在心肌桥架患者的病理生理学的最新证据.
- 概述诊断工具,用于在冠状动脉血管学期间识别特定的病原遗传机制.
- 根据已识别的致病遗传机制,讨论治疗影响.
主要方法:
- 关于心肌桥架和MINOCA的当前证据的文献综述.
- 对将MB与MINOCA联系起来的病理生理机制的分析.
- 对诊断策略和治疗方法的评估.
主要成果:
- MB可以通过表心或微血管冠状动脉,动脉硬性斑块破坏或自发冠状动脉剖析导致MINOCA.
- 对潜在机制的准确诊断对于有效的患者定制治疗至关重要.
- 冠状动脉血管学可以帮助诊断在MB患者中MINOCA的特定病理生理原因.
结论:
- 了解MB患者中MINOCA的特定机制对于指导治疗至关重要.
- 在冠状动脉血管造影期间的诊断工具可以帮助阐明MINOCA的原因.
- 个性化治疗策略是必要的,以管理与心肌架桥相关的MINOCA.
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