在FEVAR之后,年龄对外科手术前期结果的影响
Amun Georg Hofmann1, Maria Elisabeth Leinweber1, Afshin Assadian1
1Department of Vascular and Endovascular Surgery, Klinik Ottakring, Montleartstrasse 37, Pavillon 30B, 1160 Vienna, Austria.
Journal of clinical medicine
|June 10, 2023
概括
经过 fenestrated 血管内大动脉修复 (FEVAR) 的八种子体患者没有增加不良结果的风险. 作为连续因素的年龄没有影响FEVAR结果,建议将重点放在连续年龄分析上,而不是子组研究.
科学领域:
- 血管外科 血管外科
- 血管内修复 血管内修复
- 老年医学 老年医学
背景情况:
- 窗口内血管大动脉修复 (FEVAR) 是对柔和副动脉瘤的关键治疗方法.
- 之前对接受FEVAR的八十岁人群进行的研究,在不良结果方面产生了相互矛盾的结果.
- 晚年作为FEVAR结果的持续风险因素的作用需要进一步调查.
研究的目的:
- 分析年龄对FEVAR结果的影响,无论是作为一个独特的子组 (八代人) 还是连续变量.
- 为了比较80岁以上的患者和年轻患者之间的术后生存率,并发症率和技术成功.
主要方法:
- 对前性维护的FEVAR患者单中心数据库的回顾性分析.
- 八十岁患者和年轻患者的30天术后生存时间的比较.
- 使用后勤回归模型和灵敏度分析来评估年龄作为持续风险因素,并检查混因素.
主要成果:
- 八旬期患者 (95.1%) 和年轻患者 (94.3%) 之间30天生存时间没有显著差异.
- 年龄组之间的相似的并发症率和技术成功率.
- 与年轻患者 (61 ± 15 mm) 相比,八十岁患者 (67 ± 13 mm) 的动脉瘤直径更大.
- 敏感性分析证实,年龄作为连续变量并没有显著影响结果.
结论:
- 高龄人群 (八代人群) 在 FEVAR 后没有与不良的外科外科结果相关.
- 手术的时间,而不是年龄,是影响住院和ICU长度的主要因素.
- 八岁以上人群中较大的大动脉直径可能表明选择偏差;未来的研究应该关注年龄作为持续的风险因素.
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