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经IL-10工程的树突细胞调节异构的CD8+T细胞反应

Marta Fortunato1,2, Giada Amodio1, Silvia Gregori1

  • 1Mechanisms of Peripheral Tolerance Unit, San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.

International journal of molecular sciences
|June 10, 2023
PubMed
概括

经过基因工程的人类耐受性树突细胞 (tolDC) 过度表达IL-10,有效抑制细胞毒性CD8+T细胞反应. 这些IL-10工程的tolDC显示出诱导移植和T细胞介导疾病的耐受性.

关键词:
CD8+ T 细胞 CD8+ T 细胞在 IL-10 中,IL-10 是 IL-10 的代表.具有异性反应的异性反应.树突细胞是一种树突细胞.

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