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相关概念视频

Enteric Nervous System: Regulation of GI Motor Activity01:11

Enteric Nervous System: Regulation of GI Motor Activity

493
The Enteric Nervous System (ENS) plays a pivotal role in regulating gastrointestinal or GI motor activity. This complex network of nerves, deeply embedded within the gut wall, responds to changes in the gut environment and receives input from both the autonomic nervous system and the central nervous system. By doing so, the ENS operates various programs tailored to the body's nutritional status and needs.
During periods of fasting, the ENS initiates the migrating myoelectric complex, a...
493
Physiology of Enteric Nervous System and Gut Health01:05

Physiology of Enteric Nervous System and Gut Health

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The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
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Nerve Supply of the GI Tract01:27

Nerve Supply of the GI Tract

1.5K
The neuronal supply to the gastrointestinal (GI) tract is essential for regulating various functions, including digestion, absorption, and movement of food. This intricate network of nerves is known as the enteric nervous system (ENS), often referred to as the "second brain" of the body.
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of...
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Neural Regulation01:37

Neural Regulation

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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Autonomic Nervous System: Overview01:26

Autonomic Nervous System: Overview

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The human nervous system is divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and spinal cord, while the PNS contains nerve cells, clusters of nerve cells, and the sensory receptors that are outside the CNS. The PNS has two types of nerve cells: sensory (afferent) and motor (efferent). Sensory cells send signals to the CNS from receptors, and motor cells carry signals from the CNS to organs, muscles, and...
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相关实验视频

Updated: Jul 27, 2025

An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse
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An In-vitro Preparation of Isolated Enteric Neurons and Glia from the Myenteric Plexus of the Adult Mouse

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老化的肠道神经系统

Tinh Thi Nguyen1,2, Peter Baumann3, Oliver Tüscher1,4,5

  • 1Department of Psychiatry and Psychotherapy, University Medical Center Mainz, 55131 Mainz, Germany.

International journal of molecular sciences
|June 10, 2023
PubMed
概括
此摘要是机器生成的。

衰老会改变肠道的神经系统 (肠道神经系统),影响肠道功能,并可能导致阿尔茨海默氏症和帕金森症等大脑疾病.

关键词:
老化的老化 衰老的老化肠道神经系统 肠道神经系统在这里,我们可以看到子子.肠大脑轴 肠大脑轴我们的微生物群.神经退行性疾病是一种神经退行性疾病.

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相关实验视频

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科学领域:

  • 神经科学是一个神经科学.
  • 胃肠病学 胃肠病学
  • 衰老研究研究 衰老研究

背景情况:

  • 肠-大脑轴描述了胃肠道和中枢神经系统之间的双向通信.
  • 肠道受到外部因素的影响,使其衰老过程与大脑的衰老过程不同.
  • 与年龄相关的肠道功能障碍与神经退行性疾病有关.

研究的目的:

  • 审查正常细胞衰老如何影响肠道神经系统 (ENS) 的生理变化.
  • 探索ENS在与年龄相关的胃肠功能障碍和神经退行症中的作用.

主要方法:

  • 审查关于ENS衰老的现有文献.
  • 从动物模型和人体研究中分析老化ENS的形态和功能变化.

主要成果:

  • 老化的ENS表现出形态变化和退化,尽管具有可变性.
  • 肠神经系统的衰老与与年龄相关的中枢神经系统疾病有关,包括阿尔茨海默氏症和帕金森症.

结论:

  • 细胞衰老显著影响肠神经系统,导致功能变化.
  • 内脏神经系统是与年龄相关的神经退行性疾病的潜在诊断和治疗目标,因为它的可访问性.