超重或肥胖和肝硬化症的儿童的营养方法
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Chiara Spiezia1, Claudia Di Rosa1, Danilo Fintini2
1Research Unit of Food Science and Human Nutrition, Department of Science and Technology for Sustainable Development and One Health, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21-00128 Roma, Italy.
Nutrients
|June 10, 2023
概括
儿童肥胖是一个日益严重的全球性问题,增加了儿童非酒精性脂肪肝疾病 (NAFLD) 的风险. 改变生活方式,包括饮食,是管理儿科肥胖及其相关肝脏疾病的关键.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 肝病学 肝病学是一种肝病学.
- 公共卫生 营养 公共卫生 营养
背景情况:
- 儿童肥胖是一个重大的全球健康问题,影响着全球数百万人,并因COVID-19流行病等因素而恶化.
- 肥胖与众多并发症有关,尤其是非酒精性脂肪性肝病 (NAFLD),这种疾病具有复杂的病理生理学,涉及胰岛素耐药性,细胞因子信号传递和肠道微生物群失调.
- NAFLD从简单的肥胖症发展到潜在的严重结果,如肝硬化和肝细胞癌.
研究的目的:
- 审查儿科人口中肥胖和NAFLD之间的关系.
- 评估饮食模式和营养干预措施,以预防和管理儿科肥胖和NAFLD.
主要方法:
- 本综述综合了有关儿童肥胖和NAFLD的现有文献.
- 它研究了饮食,包括特定的食物成分和营养补充剂在代谢健康中的作用.
- 该审查侧重于与生活方式修改作为主要干预措施相关的证据.
主要成果:
- 饮食干预措施侧重于减少脂肪和糖摄入量,增加食纤维,有望改善儿科NAFLD的代谢参数.
- 改变生活方式,特别是减肥,是治疗儿科NAFLD的基石.
- 了解胰岛素抵抗,炎症和肠道微生物群的相互作用对于有效的管理至关重要.
结论:
- 通过饮食改变解决儿童肥胖症对于预防和管理NAFLD至关重要.
- 对儿科患者群体的特定营养策略和补充剂进行进一步的研究是有必要的.
- 将饮食,运动和潜在的向补充剂相结合的综合方法对于综合护理至关重要.
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