老年类类风湿关节炎患者的萨尔科佩尼亚和营养:一项横截面研究,以确定患病率和危险因素

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Laura Cano-García^1,2, Sara Manrique-Arija^1,2,3, Carmen Domínguez-Quesada⁴

¹Instituto de Investigación Biomédica de Málaga (IBIMA)-Plataforma Bionand, 29010 Málaga, Spain.

Nutrients

|June 10, 2023

概括

老年类类风湿性关节炎 (RA) 患者面临更高的肉症和营养不良的风险. 男性性别,更长的疾病持续时间和营养状况不佳是RA中缩症的关键风险因素.

科学领域:

老年学是一门学科.
类风湿病学类风湿病学
营养科学营养科学

背景情况:

类风湿性关节炎 (RA) 是一种慢性炎症性疾病,影响关节.
患有RA的老年人容易发生与年龄相关的肌肉损失 (肉症).
了解老年RA患者的麻症患病率和风险因素对于有针对性的干预至关重要.

研究的目的:

为了确定65岁及以上的RA患者中肉类症的患病率.
在此RA患者队列中识别与肉类相关的危险因素.

主要方法:

一项多中心的横截面研究比较了76名RA患者与76名年龄和性别匹配的健康对照.
使用EWGSOP2标准诊断出了肉类.
采用全身双能X射线吸收度 (DXA) 和二进制回归分析.

主要成果:

与对照组相比,RA患者的肌肉质量较低,脂肪度较高.
麻症在15.8%的RA患者中被诊断为麻症,而对照组为3.9% (p=0.014).
在RA患者中,肉症的危险因素包括男性性别 (OR 9.3),较长的疾病持续时间 (OR 1.1),以及较差的营养状况 (MNA评分,OR 0.7).

结论:

高龄的RA患者患有缩症,肥胖增加和营养不良的风险较高.
长期疾病和营养状况不佳的男性RA患者特别容易受到伤害.
这些发现强调了在老年RA人群中积极查和治疗肉类的必要性.

关键词:

身体构成身体组成年长的老人老年人老年人.营养不良营养不良营养不良营养营养营养营养肥胖肥胖肥胖肥胖肥胖肥胖肥胖肥胖类风湿性关节炎类风湿性关节炎这种类型的麻症是sarcopenia.

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