了解人类肠道微生物群的进步及其对儿科腹腔疾病的影响 - - 一篇叙述性评论
Vasile Valeriu Lupu1, Laura Mihaela Trandafir1, Anca Adam Raileanu1
1Department of Pediatrics, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Nutrients
|June 10, 2023
概括
乳病 (CD) 涉及遗传学和质,但肠道细菌也起着关键作用. 调节肠道微生物群可能为CD提供新的预防和治疗策略.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
- 微生物学 微生物学
背景情况:
- 乳病 (CD) 是由于遗传倾向和质暴露而产生的.
- 环境因素,特别是肠道微生物群,在CD的发病过程中起到共同的作用.
- 早期生活因素,如出生方式和养影响微生物组和CD风险.
研究的目的:
- 审查肠道微生物群参与CD的机制.
- 探索微生物群调制用于CD预防和治疗.
主要方法:
- 关于乳病和肠道微生物群的研究的文献综述.
- 对CD患者的细菌,病毒和真菌失生症的分析.
- 对诸如益生菌,益生菌和便微生物移植等干预措施的评估.
主要成果:
- 疾病与增加的格拉姆阴性细菌 (Bacteroides,Escherichia,Prevotella) 和减少的有益细菌 (乳酸细菌,Bifidobacteria) 有关.
- 病毒和真菌失生症也在CD中观察到.
- 无质饮食可以改善症状,但不能解决肠道疾病.
结论:
- 肠道微生物群的变化在乳病的发病过程中具有重要意义.
- 针对微生物群的治疗方法有希望,但需要进一步研究,特别是在儿科CD患者中.
相关概念视频
Anatomy of the Intestines
72.6K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.6K
What is Monogastric Digestion?
71.7K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.7K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
362
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
362
Microorganisms in Medicine and Therapeutics
72
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
72


