肠-大脑相互作用障碍和神经性厌食症:精神病学资产,厌恶和胃肠道症状
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Assessing Activity-based Anorexia in Mice
Published on: May 14, 2018
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Luna Carpinelli1, Giulia Savarese1, Biagio Pascale1
1Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", Baronissi Campus, University of Salerno, 84081 Baronissi, Italy.
Nutrients
|June 10, 2023
概括
神经性厌食症患者经常出现肠-大脑相互作用障碍,功能性消化不良和刺激性肠综合征的发病率很高. 精神病理因素和厌恶与这些胃肠道症状有显著的相关性.
科学领域:
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
- 心理学 心理学 心理学
背景情况:
- 胃肠道 (GI) 症状在患有饮食障碍 (ED) 的个体中很普遍.
- 肠-大脑相互作用障碍 (DGBIs) 是ED中常见的并发症.
- 了解AN,DGBI和精神病理学之间的相互作用至关重要.
研究的目的:
- 通过使用ROME IV标准来确定神经性厌食症 (AN) 患者中DGBI的患病率.
- 调查心理病理因素和厌恶对AN的胃肠道症状的影响.
- 探索AN,DGBI和心理困扰之间的关系.
主要方法:
- 38名女性AN患者完成了验证的调查问卷,评估了心理病理 (EDI-3,HADS,SPAS,BUT) 和厌恶 (DS).
- DGBI的诊断是根据ROME IV标准进行的.
- 用标准化强度-频率问卷评估了胃肠道症状.
主要成果:
- 观察到DGBI的高患病率:94.7%符合功能性消化不良症 (FD) 的标准,52.6%符合刺激性肠综合征 (IBS),7.9%符合功能性便秘 (FC).
- 所有参与者都在厌恶度表上获得了病理性得分.
- 在胃肠道症状和精神病理特征之间发现了显著的相关性,包括厌恶.
结论:
- 神经性厌食症是一种复杂的疾病,与DGBIs有显著的重叠.
- 针对DGBI和情感认知结构的综合治疗方法对于管理AN至关重要.
- 进一步的研究应该探索AN的多面性质,包括DGBI和心理因素.
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