母亲对甜味的遗传偏好与母婴偏好和摄入量有关
Pernilla Lif Holgerson1, Pamela Hasslöf1, Anders Esberg2
1Department of Odontology, Section of Pediatric Dentistry, Faculty of Medicine, Umeå University, SE-90185 Umeå, Sweden.
Nutrients
|June 10, 2023
概括
母亲的甜味偏好和摄入量受到遗传因素的影响. 母亲和儿童的特定基因变异 (SNP) 与较高的甜食摄入量和偏好有关,影响BMI.
科学领域:
- 遗传学 遗传学 是一个
- 营养科学 营养科学
- 人体生理学 人体生理学
背景情况:
- 味觉感知显著影响食物选择和摄入.
- 味觉受体和传递器的遗传变异会影响个体的味觉敏感性.
- 母亲的饮食习惯和遗传倾向可以影响后代的饮食行为.
研究的目的:
- 调查母亲遗传因素对甜味偏好和摄入量的影响.
- 为了确定孩子是否表现出与母亲相似的甜食摄入模式或相关特征.
- 确定与母婴对的甜味偏好和摄入量相关的特定遗传变异.
主要方法:
- 在与饮食偏好相关的基因中测序133个单核酸多态 (SNP).
- 从187对母亲和孩子的唾液样本中进行DNA分析.
- 饮食摄入量和口味偏好评估使用甜味,苦味,酸味和乌玛米食品的问卷.
主要成果:
- 32种SNP变体与甜味偏好或摄入量 (p <0.05) 有关.
- 两个SNP,rs7513755 (TAS1R2基因) 和rs34162196 (OR10G3基因),通过了多次测试校正 (q <0.05).
- rs34162196的T等位基因与母亲和儿童的较高甜食摄入量以及较高的母亲BMI相关. rs7513755的G基因组与母亲增加的甜食偏好有关.
结论:
- 遗传因素在母亲的甜味偏好和摄入中发挥作用,并可能产生代际影响.
- rs34162196 SNP是开发基因评分来评估甜食摄入量的潜在候选者.
- 了解对口味偏好的遗传影响,可以为饮食管理和公共卫生策略提供信息.
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