膀癌的囊切除术后的30天不良事件与良性膀疾病相比
Malte W Vetterlein1,2, Thomas Seisen1,3, Jacqueline Speed1
1Division of Urological Surgery and Center for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Urology practice
|June 10, 2023
概括
与癌症病例相比,治疗良性膀疾病的囊切除术会导致更长的住院时间和更复杂的出院. 这可能是由于手术前患者健康状况较差,需要量身定制的康复计划.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 外科手术的结果
- 在瘤学瘤学.
背景情况:
- 囊切除术是肌肉侵入性膀癌的首要治疗方法,也是良性膀疾病的最后手段.
- 癌症和良性疾病中囊切除术的外科治疗结果尚不清楚.
研究的目的:
- 为了比较膀癌的囊切除术30天周围手术结果与良性疾病.
- 根据囊管切除术的适用性,确定影响结果的因素.
主要方法:
- 利用了国家外科质量改进计划数据库 (2006-2013).
- 提取了接受囊切除术的患者的数据.
- 进行双变量和多变量逻辑回归分析,以根据指示评估结果.
主要成果:
- 分析了3,166例癌症和248例良性疾病的囊切除术.
- 由于良性疾病而接受囊切除术的患者年轻,但功能状况较差,并患有更多的并发症 (败血症,).
- 经过调整后的分析显示,没有癌症的患者在长期住院 (OR 2.14) 和退院到特殊护理机构 (OR 3.08) 的几率明显更高.
结论:
- 治疗良性疾病的囊切除与长时间住院和不良出院的风险增加有关.
- 在良性群体中,基线功能状况和并发症的恶化可能会导致这些较差的结果.
- 考虑到患者基线特征的个性化术后护理途径可能会改善囊切除术后的结果.
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