在社区实践泌尿器科中探索米托米C使用模式
Matthew Mossanen1, Matthew D Ingham1, Jeffrey J Leow1,2
1Division of Urology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Urology practice
|June 10, 2023
概括
膀瘤切除后的米托米C使用量增加,但仍然很低. 老年患者和那些患有更多并发症的人不太可能接受它,而高体积的外科医生更有可能进行这种治疗.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 证据支持使用mitomycin C在通过尿道切除膀瘤后,以减少复发.
- 限量采用mitomycin C强调需要探索护理模式和障碍.
- 索赔数据分析可以揭示社区泌尿外科实践中mitomycin C利用的趋势.
研究的目的:
- 分析社区泌尿病学中mitomycin C使用的当代趋势.
- 为了识别与米托米辛C的管理相关的患者,医院和外科特征.
- 评估年龄和并发症对米托米辛C使用的影响.
主要方法:
- 来自Premier医院数据库 (2003-2015) 的当代基于人口的队列的分析.
- 包括接受过尿道膀瘤切除的患者.
- 多变量后勤回归用于评估与患者,医院和手术因素的关联,包括年龄和并发症.
主要成果:
- 线粒素C的使用量从3.3% (2003年) 增加到5.5% (2013年),然后下降到4.5% (2015年).
- 老年患者 (≥65岁) 和具有较高查尔森并发症指数的患者表现出与线粒素C使用的不同关联.
- 较高的年度外科医生数量与增加的线粒素C使用显著相关 (OR 1.68).
结论:
- 在临床实践中,尽管发生了适度增加,但米托米辛C在临床实践中仍未得到充分利用.
- 患有较大的并发症的患者不太可能接受米托米辛C.
- 高体积的外科医生更有可能给出mitomycin C,这表明实践的变化.
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