昏迷分数与新一代设备测量的血图参数之间的关系
Erdogan Duran1,2, Basak Pehlivan1,2, Ismail Koyuncu
1Department of Anaesthesiology and Reanimation, Medicine Faculty, University of Harran, Sanliurfa, Turkiye.
概括
较新的血液学参数,如%MAC和IG与ICU患者的昏迷得分相关,具有作为快速预后生物标志物的潜力. 这些发现可能有助于开发重症监护的新型评分系统.
科学领域:
- 关键护理医学 关键护理医学
- 血液学 血液学 血液学
- 临床病理学 临床病理学
背景情况:
- 昏迷评分 (格拉斯哥昏迷量表 - GCS,序列器官衰竭评估 - SOFA,急性生理和慢性健康评估 - APACHE-II) 对于评估重症监护病房 (ICU) 患者的严重程度至关重要.
- 血液学参数可以提供对患者预后和潜在生理状况的见解.
研究的目的:
- 为了研究各种昏迷得分 (GCS,SOFA,APACHE-II) 和ICU患者的特定血液学参数之间的关联.
- 评估新型血液学标志物的潜力,作为重症监护中的预后指标.
主要方法:
- 对ICU患者和健康的对照组进行了一项描述性比较研究.
- 使用AlinityHQ自分析仪分析了血液图参数,并与GCS,SOFA和APACHE-II得分进行了比较.
主要成果:
- 在不成熟粒细胞 (IG),百分比宏细胞 (%MAC) 和血小板分布宽度 (PDW) 值中发现了统计学上显著的差异,显示了与GCS得分的反相关性.
- 在SOFA得分和%高染色比率 (%HPR) /细胞血红蛋白度 (cHGB) 和APACHE-II得分和核红细胞 (NRBC) /核红细胞/白细胞比率 (NR/W) 之间也观察到显著的相关性.
结论:
- 血液学参数如%MAC,IG,cHGB,NRBC,NR/W和%HPR,通过新一代设备测量,与昏迷得分相关.
- 这些参数显示出在ICU环境中作为简单,快速的预后生物标志物的潜力.
- 这些发现可能有助于为重症监护患者开发新的评分模型.
相关概念视频
01:30Equipments Used To Measure Blood Pressure
Direct Method
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
01:17Measurement of Blood Pressure
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.