病毒性肝炎引起的慢性肝病,COVID-19住院治疗和死亡率之间的关联
Javaria Aslam1, Fahad Qaisar2, Mutahra Khaliq2
1Department of Medicine, Sir Sadiq Abbasi Hospital Bahawalpur, Qauid-e-Azam Medical College, Bahawalpur, Pakistan.
概括
由于病毒性肝炎而患有慢性肝病 (CLD) 的患者不太可能因COVID-19住院. 与其他并发症患者相比,CLD患者也经历了COVID-19的严重程度和死亡率的降低.
科学领域:
- 肝病学和传染病的研究
- 流行病学和公共卫生.
背景情况:
- 慢性肝病 (CLD) 对COVID-19结果的影响仍然是一个引人注目的领域.
- 病毒性乙型肝炎和乙型肝炎是全球CLL的主要原因,需要了解它们在COVID-19等传染病背景下的作用.
研究的目的:
- 调查病毒性肝炎导致的慢性肝病 (CLD) 与COVID-19住院治疗之间的关联.
- 为了评估之前的CLD状态的患者中严重的COVID-19疾病进展和死亡率的风险.
主要方法:
- 一项队列研究于2021年7月至12月在巴基斯坦进行.
- 该研究将CVD患者的COVID-19住院率与一般人口进行了比较,使用非COVID医疗入院作为对照.
- 亚组分析检查了COVID-19患者中患有或没有CLD的疾病严重程度和死亡风险.
主要成果:
- 总共分析了3,976名参与者. 患有CLD的患者的COVID-19住院可能性显著降低 (1.7%与8.8%相比).
- 在COVID-19入院患者中,与其他并发症患者相比,CLD与死亡风险降低有关 (14.8%与36.9%对比).
- 由于COVID-19而入院的CLD患者的死亡风险低于因非COVID CLD相关并发症而入院的患者 (14.8%vs35.1%).
结论:
- 由病毒性肝炎引起的慢性肝病与COVID-19住院的可能性降低有关.
- 与其他并发症患者相比,患有CLD的患者患重症COVID-19和相关死亡率的风险较低.
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