在患有慢性脏病的老年患者中,sarcopenia和虚弱之间存在关联
Che Wang1,2, Xinru Guo1,2, Xieguanxuan Xu1
1Department of Nephrology, The First Medical Centre, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Beijing, China.
Journal of cachexia, sarcopenia and muscle
|June 10, 2023
概括
萨科佩尼亚与慢性病 (CKD) 的老年患者的脆弱性有关. 建议对患者进行早期的脆弱性评估,这些患者有sarcopenia,晚年,高CKD阶段,腰部部比率增加和低血清白蛋白.
科学领域:
- 老年学是指老年学的学科.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年医学 老年医学
背景情况:
- 慢性病 (CKD) 患者常见的脆弱性和性,增加不良健康风险.
- 在非透析的CKD患者中,关于虚弱性-sarcopenia联系的研究有限.
研究的目的:
- 确定与老年CKDI-IV阶段患者虚弱相关的因素.
- 为了能够在这个人群中早期识别和干预脆弱性.
主要方法:
- 一个脆弱指数 (FI) 模型被用于评估774名老年CKD患者 (I-IV阶段) 的脆弱风险.
- Sarcopenia 的定义是使用亚洲 Sarcopenia 2019 工作组的标准来定义的.
- 多项逻辑回归分析了与脆弱相关的因素.
主要成果:
- 在774名参与者 (平均年龄67岁) 中,肉类的患病率为30.6%.
- 麻症,晚年,CKDII-IV阶段,低血清白蛋白和腰部部比率增加与高FI有关.
- 晚年和CKD阶段III-IV与FI的中位数相关.
结论:
- 皮症是老年CKD患者 (I-IV阶段) 虚弱的独立危险因素.
- 建议对患有肉类症,晚年,高CKD阶段,高腰部比率和低血清白蛋白的患者进行脆弱性评估.
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