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用于膜脊保护的乳矩阵衍生:一个随机对照试验

Momen A Atieh^1,2, Bashayer Al-Ali¹, Maanas Shah¹

¹Mohammed Bin Rashid University of Medicine and Health Sciences, Hamdan Bin Mohammed College of Dental Medicine, Dubai Healthcare City, Dubai, United Arab Emirates.

Clinical oral implants research

|June 10, 2023

概括

使用脱蛋白牛骨矿物质 (DBBM) 与质矩阵衍生物 (EMD) 或单独使用DBBM进行膜脊保护 (ARP) 在放射测量中没有显著差异. 然而,与EMD一起的DBBM更好地保持了脊梁高度,而单独的DBBM则减少了手术后的不适.

科学领域:

牙科手术是指牙科手术.
牙周病学牙周病学
再生医学是一种再生医学.

背景情况:

牙拔牙后,膜脊 (ARP) 的保存至关重要,以保持骨体积.
脱蛋白牛骨矿物质 (DBBM) 是ARP的常见移植材料.
乳矩阵衍生物 (EMD) 可能增强骨再生.

研究的目的:

为了比较放射性维度变化和患者报告的ARP使用DBBM与EMD与单独使用DBBM的结果.
评估DBBM与EMD在保持膜脊高度和宽度方面的有效性.
为了评估患者在ARP后的舒适度,使用两个不同的生物材料.

主要方法:

一项随机临床试验,涉及18名参与者接受牙拔除和ARP.
两个治疗组:ARP与DBBM/EMD或ARP与单独的DBBM.
在基线和6个月的圆束计算机断层扫描 (CBCT) 扫描以测量膜脊高度 (ARH) 和宽度 (ARW).

主要成果:

在6个月后,DBBM/EMD和单独DBBM组之间的平均ARH和ARW没有统计学上显著的差异.
与单独使用DBBM (14.3%) 相比,在DBBM/EMD组中 (54.5%) 的部位显著更高的百分比显示了最小的ARH损失 (<1mm).
患者报告DBBM单独组在前两天显著减少伤,出血和疼痛.

结论:

对ARH和ARW的放射平均测量在ARP与DBBM/EMD和单独DBBM之间没有显著差异.
带有EMD的DBBM表现出一种趋势,即更好地保持膜脊高度.
单独的DBBM与早期术后患者舒适度的改善有关.

关键词:

鼓膜脊的保护鼓膜脊的保护没有蛋白质的牛骨矿物质.质矩阵衍生品的衍生品患者报告的结果措施.随机对照试验是随机对照试验.

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