社区药房的处方模式和相关因素:使用AWaRe分类和世卫组织抗生素处方指标的跨部门研究在埃塞俄比亚的Dire Dawa,埃塞俄比亚
Beyene Dereje1, Alemseged Workneh2, Alemayehu Megersa2
1Department of Pharmacology, School of Medicine, College of Medicine and Health Sciences, Dire Dawa University, Dire Dawa, Ethiopia. beyexderie23@gmail.com.
Drugs - real world outcomes
|June 10, 2023
概括
社区药房的抗生素处方量很高,超过了世卫组织的标准. 患者的年龄,性别和药物数量都会影响抗生素的使用,这凸显了合理的处方实践的必要性.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 抗微生物药物可以驱动耐药性,需要谨慎的处方,分发和管理.
- AWaRe分类 (访问,观察,储备) 将抗生素分类,以促进合理使用.
- 了解处方模式和影响抗生素使用的因素对于制定有效的指南至关重要.
研究的目的:
- 根据世卫组织指标和AWaRe分类,评估社区药房的抗生素处方做法.
- 确定与抗生素使用和其流行率相关的因素.
- 为改善合理使用药物提供证据.
主要方法:
- 在七家社区药房进行了前性和横截面研究.
- 在2022年10月1日至31日期间,使用分层随机抽样审查了1200次遭遇.
- 数据使用SPSS版本27进行分析,以评估处方实践和相关因素.
主要成果:
- 抗生素在47.8%的遭遇中被处方,其中43.1%来自Watch组.
- 患者年龄 (年轻患者更有可能),性别 (男性更有可能),以及药物数量 (与更高可能性相关的两种以上药物) 显著影响了抗生素处方.
- 抗生素处方的几率随着每种额外的药物处方而增加.
结论:
- 社区药房的抗生素处方率明显超过了世卫组织的标准.
- 虽然Access组的抗生素使用略低于世卫组织的建议,但整体处方需要优化.
- 处方模式与患者人口统计和药物治疗方案的复杂性有显著的相关性,这强调了针对性干预的必要性.
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