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相关实验视频

Updated: Jul 27, 2025

A Rapid, Multiplex Dual Reporter IgG and IgM SARS-CoV-2 Neutralization Assay for a Multiplexed Bead-Based Flow Analysis System

A Rapid, Multiplex Dual Reporter IgG and IgM SARS-CoV-2 Neutralization Assay for a Multiplexed Bead-Based Flow Analysis System

Published on: April 6, 2021

便携式微流体阻抗生物传感器用于SARS-CoV-2检测.

Soroush Laleh¹, Bergoi Ibarlucea², Marlena Stadtmüller³

¹Micro- and NanoBiomedical Engineering Group (MNBE), Institute for Emerging Electronic Technologies, Leibniz Institute for Solid State and Materials Research (Leibniz IFW Dresden), 01069, Dresden, Germany; Chair of Micro- and NanoSystems, Center for Molecular Bioengineering (B CUBE), Dresden University of Technology, 01062, Dresden, Germany.

Biosensors & bioelectronics

|June 10, 2023

概括

这项研究介绍了一种新的微流体生物传感器,用于快速,便携式检测SARS-CoV-2,从而能够早期诊断COVID-19. 该设备为患者样本提供可靠的结果,推进点诊断诊断.

关键词:

在COVID-19诊断中使用的诊断方法.电化学检测电化学检测电化学阻抗光谱学电化学阻抗光谱学护理中心的关心点在SARS-CoV-2生物传感器中.

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Last Updated: Jul 27, 2025

A Rapid, Multiplex Dual Reporter IgG and IgM SARS-CoV-2 Neutralization Assay for a Multiplexed Bead-Based Flow Analysis System

A Rapid, Multiplex Dual Reporter IgG and IgM SARS-CoV-2 Neutralization Assay for a Multiplexed Bead-Based Flow Analysis System

Published on: April 6, 2021

Author Spotlight: Advancing Pathogen Diagnostics with Standardized LAMP

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Author Spotlight: High-Quality Quantum Dot Nanobeads for Sensitive Fluorescent Lateral Flow Immunoassays

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科学领域:

生物医学工程生物医学工程
纳米技术纳米技术
传染病诊断传染病诊断传染病诊断

背景情况:

当前的流行病威胁需要快速,可访问的诊断工具.
标准的聚合酶连锁反应 (PCR) 是准确的,但缓慢,昂贵,需要专门的设施.
需要小型,便携式传感器,用于早期检测病原体和疾病监测.

研究的目的:

开发一个敏感的微流体阻抗生物传感器,用于直接检测SARS-CoV-2.
创建一个移动点的护理 (POC) 平台,用于快速诊断.
能够及早检测病原体,并监测病毒载量.

主要方法:

使用实验设计 (DoE) 优化操作参数.
利用电化学阻抗光谱 (EIS) 进行病毒抗原检测.
经过验证的生物传感器性能与尖的缓冲样本和真实患者样本 (Ct至27).

主要成果:

在女性体 (fM) 度水平上实现了SARS-CoV-2的敏感检测.
用真实患者样本证明了生物传感器的功能.
展示了平台的多功能性,包括便携式电源控制器和基于智能手机的读数.

结论:

开发的微流体生物传感器为COVID-19诊断提供了快速,可靠和便携式的解决方案.
该平台的适应性支持扩展到其他传染病.
为了疾病管理,方便在不同人群中监测病毒载量.