发育过程中的热应激中断了精子生成,导致Drosophila melanogaster的早期男性不育
Berta Canal Domenech1, Claudia Fricke2
1Institute for Evolution and Biodiversity, University of Muenster, Muenster, Germany; Muenster Graduate School of Evolution, University of Muenster, Muenster, Germany.
Journal of thermal biology
|June 10, 2023
概括
热应激特别影响雄性果的精子发育的最后阶段,延迟生育能力. 了解这种热敏度对于预测物种至关重要.
科学领域:
- 生殖生物学 生殖生物学
- 环境压力生理学生理学
- 发展生物学 发展生物学
背景情况:
- 热应激显著降低了男性的生育能力,对物种的持续存在带来了生态和进化风险.
- 低于致命的温度可能会导致暂时不育和体能丧失.
- 识别男性生殖过程中热敏发育阶段至关重要.
研究的目的:
- 为了确定哪个发育阶段在雄性Drosophila melanogaster中对热应激最敏感.
- 为了研究热暴露后生育能力恢复的机制.
- 了解热量对精子生成和男性生殖潜力的影响.
主要方法:
- 在特定的发育阶段,对雄性Drosophila melanogaster进行热应激的实验暴露.
- 早期男性生殖能力和生育能力恢复动态的评估.
- 分析丸内的精子生产和成熟过程.
主要成果:
- 精子生成的后期阶段,特别是幼阶段,对热应激非常敏感.
- 暴露于热量显著中断精子的生产和成熟,导致延迟生育能力.
- 测量丸功能和精子可用性证实了因热引起的生殖能力延迟.
结论:
- 幼发育阶段是男性果生育热敏度的关键窗口.
- 热应激扰乱了精子生成的重要过程,影响了男性的生殖成功.
- 了解这些机制对于评估气候变化对昆虫种群的影响至关重要.
相关概念视频
02:27Background and Environment Affect Phenotype
6.6K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.6K
01:41Spermatogenesis
102.7K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
102.7K