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Updated: Jul 27, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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基于结构的虚拟查发现了强效和选择性的腺A1受体对手

Pierre Matricon1, Anh Tn Nguyen2, Duc Duy Vo1

  • 1Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, SE-751 24, Uppsala, Sweden.

European journal of medicinal chemistry
|June 10, 2023
PubMed
概括

基于结构的虚拟查确定了选择性的A1腺素受体 (A1R) 配体. 这种方法成功引导了强效和选择性的A1R抗剂的设计,为更安全的药物开发铺平了道路.

关键词:
计算机辅助药物设计与G蛋白结合受体的受体是G蛋白结合的受体.分子对接是分子对接.选择性的选择性

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