美国肺部CT查报告和数据系统ACR肺部CT查报告和数据系统,在美国预防性服务工作组资格标准变化之前进行系统审查和元分析:2014年至2021年
Joey Z Gu1, Grayson L Baird2, Connie Ge3
1Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Journal of the American College of Radiology : JACR
|June 10, 2023
概括
肺CT查结果显示,肺RADS得分和正预测值 (PPV) 与ACR估计值不同. 这表明重新评估真实世界肺癌查人群的肺-RADS分类.
科学领域:
- 放射学和成像学 放射学和成像学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 肺CT查报告和数据系统 (Lung-RADS) 对于标准化肺癌查解释至关重要.
- 了解肺RADS的现实性能至关重要,尤其是在查资格标准的潜在变化之前.
- 美国放射学学院 (ACR) 之前的估计为预期的肺RADS得分分布和正预测值 (PPV) 提供了基准.
研究的目的:
- 从2014年到2021年,系统地审查和元分析肺-RADS得分和PPV.
- 为了比较真实世界的肺RADS数据与美国放射学学院 (ACR) 的估计.
- 为完善肺-RADS分类提供洞察力.
主要方法:
- 一项系统性审查和对报告美国低剂量CT (LDCT) 肺癌查中的肺RADS研究的元分析.
- 包括2014-2021年的数据,包括24项研究和32817例患者接触.
- 用于对肺RADS得分和PPV的元分析的通用线性混合建模.
主要成果:
- 分析显示,与ACR指南相比,肺-RADS 1-2分数 (84.4%) 低于预期,肺-RADS 3分数 (8.7%) 和4分数 (6.5%) 高于预期.
- 对肺RADS 3-4的总体观察到的PPV为13.1%,低于ACR的最低估计21%.
- 肺RADS 4的PPV为28.6%,与ACR的最低估计一致.
结论:
- 目前关于肺RADS得分和PPV的文献数据与ACR估计不一致.
- 重新检查肺-RADS分类可能是必要的,以改善与真实世界肺癌查人群的一致性.
- 这项研究在实施更广泛的查指南之前提供了有价值的基准,并为未来的报告实践提供了信息.
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