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在慢性不可预测压力斑马鱼模型中对Andrographis paniculata Nees提取物和andrographolide进行抗抑郁药的评估

Zenab Aldurrah1, Farah Syazwani Mohd Kauli2, Nurhidayah Abdul Rahim2

  • 1Discipline of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia. Electronic address: https://twitter.com/zenab_aldurrah.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
|June 10, 2023
PubMed
概括

在斑马鱼模型中,Andrographis paniculata提取物和andrographolide在慢性不可预测的压力中表现出抗抑郁作用. 安德罗格拉福利德显著降低了压力行为和皮质醇水平,这表明它有可能成为一种新的抗抑郁药疗法.

关键词:
安德罗格拉菲斯 (Andrographis paniculata) 是一个恐慌的动物.安德罗格拉福利德 (Andrographolide) 是一种色蛋白质.行为测试 行为测试慢性不可预测的压力.皮质醇分析 皮质醇分析有毒性测试 有毒性测试

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